8355 County Rd 621 Cape Girardeau Missouri 4 bedroom 4 bathroom home for sale listed at $2,500,000
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ACTIVEPool
$2,500,000
MLS# MIS26061848

8355 County Rd 621

Cape Girardeau, MO 63701· Cape Girardeau County
NA
52.5
Acres
4
Bedrooms
Country Home
Type
4
Bathrooms
7,050 sf
Home Sq Ft
1994
Year Built
$4,927/yr
Est. Taxes
0 Days
On Market
October 20, 2026
Listed

About This Property

This property is a true unicorn!....Welcome home to a stunning residence nestled on 52 acres close to Cape and in Jackson School District! Built with care and love, this special home boasts so much craftsmanship with an eye for detail--coffered and beamed ceilings, solid wood doors and moldings, and large rooms with gorgeous views into nature. The kitchen, as well as the entire home, allows for large gatherings, yet feels cozy on a snowy day. There is plenty of summertime fun to be had in the pool area, and the oversized driveway near the house can function as ample car parking when hosting large parties. There is lots of blooming landscaping to enjoy as well as the natural woods on this expansive property. With newer HVAC and roof, you can move right in!

Land & Acreage

Property TypeResidential (Home on Acreage)
SubtypeSingle Family Residence
Acreage52.50 acres
Lot Sq Ft2,286,900 sq ft
CountyCape Girardeau County
Parcel Number10-901-26-00-02800-0000
SubdivisionNA

Land Features & Use

Terrain & Lot Features
Back Yard

Water & Utilities

Sewer / SepticSeptic Tank
ElectricAmeren
UtilitiesCable Available, Electricity Available, Natural Gas Available, Water Available

The Home

Bedrooms4
Bathrooms Full3
Bathrooms Half1
Living Area7,050 sq ft
Year Built1994
LevelsOne
StyleTraditional
ConstructionBrick
HeatingElectric
CoolingCeiling Fan(s)
FireplaceYes (2)
BasementPartially Finished, Full, Walk-Out Access
Garage3.0 Car
Interior Features
Beamed CeilingsBookcasesCathedral Ceiling(s)Special Millwork
Appliances
Electric CooktopENERGY STAR Qualified DishwasherDisposalDouble OvenWater Softener
Patio & Porch
EnclosedFront PorchPatio

Financial & Terms

List Price$2,500,000
Original Price$2,500,000
Annual Taxes$4,927 (2025)
Listing TermsCash, Contract, Conventional
PossessionClose Of Escrow

About Cape Girardeau County

Southeast Lowlands (Bootheel)
Land & Farm

Where the Bootheel meets the hills — cropland and deer woods.

Cape Girardeau County marks the northern gateway to the Bootheel, where the flat lowlands meet the rising Ozark escarpment along the Mississippi River. This is the region's most varied ground: fertile bottomland along the river and the Whitewater and Castor drainages gives way to rolling, timbered hills to the west. That mix suits buyers who want both worlds — productive cropland of soybeans, corn, and wheat in the bottoms, and wooded uplands that hold whitetail and turkey. Rivers and creeks thread the county, adding waterfowl to the flooded lowlands and fishing to the mix. For a land buyer seeking farm income and genuine hill-country hunting within reach of the delta, Cape Girardeau offers the fullest blend in southeast Missouri.

Terrain
River bottoms rising to rolling Ozark hills
Land Use
Bottomland row crops with upland timber and pasture
Water
Mississippi, Whitewater, and Castor rivers
Recreation
Whitetail, turkey, waterfowl, and fishing
Area overview for general orientation — verify specifics independently.
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Listing information is deemed reliable but not guaranteed and should be independently verified. IDX information provided by MARIS MLS. Listing courtesy of Area Properties Real Estate-River Region. Listed by Sharon Mueller.

MLS# MIS26061848 · Key: MIS208416739 · Last updated: Oct 20, 2026

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